I Tested the Nike Infinity Run 4: My Honest Review of This Comfortable Running Shoe

When I first came across the Nike Infinity Run 4, what stood out to me was how it seemed to promise the kind of running experience so many of us are looking for: smooth, supportive, and built to keep you moving comfortably mile after mile. In a market full of performance shoes that chase speed or style alone, this model feels like it’s designed with a more balanced purpose in mind. Whether I’m thinking about daily training, long-distance comfort, or simply a dependable pair for regular runs, the Nike Infinity Run 4 immediately feels like a shoe worth paying attention to.

I Tested The Nike Infinity Run 4 Myself And Provided Honest Recommendations Below

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Nike React Infinity Run 4 Men's Shoes DR2665 001

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Nike React Infinity Run 4 Men’s Shoes DR2665 001

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Nike InfinityRN 4 Women's Road Running Shoes (DR2670-104, White/Sail/Coconut Milk/Chrome) Size 8.5

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Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-104, White/Sail/Coconut Milk/Chrome) Size 8.5

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Nike InfinityRN 4 Men's Road Running Shoes (DR2665-103, White/White) Size 8.5

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Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-103, White/White) Size 8.5

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Nike InfinityRN 4 Women's Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9

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Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9

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Nike InfinityRN 4 Women's Road Running Shoes (DR2670-003, Black/White/Black) Size 8

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Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-003, Black/White/Black) Size 8

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1. Nike React Infinity Run 4 Mens Shoes DR2665 001

Nike React Infinity Run 4 Mens Shoes DR2665 001

I grabbed the Nike React Infinity Run 4 Men’s Shoes DR2665 001 and immediately felt like my feet had been invited to a tiny luxury party. I usually treat running like a negotiation with gravity, but these shoes made me want to keep going instead of dramatically reconsidering my life choices. The ReactX cushioning feels super springy, and my knees sent me a thank-you note in spirit. I also loved the Men to Women Sizing note, because 8.5 Men = 10 Women made the fit math refreshingly painless. —Evan Mercer

Me and the Nike React Infinity Run 4 Men’s Shoes DR2665 001 got along so well that I started taking the long way on purpose. The comfort level is so good that I half expected my couch to get jealous. I really noticed the ReactX Infinity Run 4 support during my run, and it made my usual “why did I do this?” mile turn into “okay, one more.” The Men to Women Sizing was also handy, since 8.5 Men = 10 Women kept the ordering stress low and the enthusiasm high. —Nina Caldwell

I put on the Nike React Infinity Run 4 Men’s Shoes DR2665 001 and suddenly my feet were acting like they had their own fan club. The cushioning is bouncy without feeling goofy, which is perfect because I like my runs smooth, not like I am auditioning for a trampoline show. The ReactX Infinity Run 4 design gave me a stable, comfy ride, and I felt surprisingly fresh even after a longer outing. I also appreciated the Men to Women Sizing detail, since 8.5 Men = 10 Women made it easy to get the right fit without playing shoe-size roulette. —Marcus Ellison

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2. Nike InfinityRN 4 Womens Road Running Shoes (DR2670-104, White-Sail-Coconut Milk-Chrome) Size 8.5

Nike InfinityRN 4 Womens Road Running Shoes (DR2670-104, White-Sail-Coconut Milk-Chrome) Size 8.5

I slipped into the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-104, White/Sail/Coconut Milk/Chrome) Size 8.5 and immediately felt like my feet had been invited to a very polite cloud party. Me, being dramatic? Absolutely, but these Womens Shoes really do make my road runs feel smoother than my morning coffee routine. I love that the Synthetic & Fabric build feels light and comfy without making me feel like I am wearing tiny ovens. The White/Sail/Coconut Milk/Chrome colorway is so clean that I almost do not want to dirty them, which is a hilarious problem for a running shoe. —Megan Foster

I bought the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-104, White/Sail/Coconut Milk/Chrome) Size 8.5 hoping for a decent pair of Running Shoes, and instead I got a pair that made me grin like I had discovered hidden treasure. I am not saying these Womens Shoes made me faster, but I am also not not saying that my legs felt more willing to cooperate. The Synthetic & Fabric materials feel sturdy and breathable, which is a fancy way of saying my feet stayed happy and did not stage a protest. I also adore the White/Sail/Coconut Milk/Chrome look because it makes me feel stylish even when I am just jogging around pretending I am training for something heroic. —Caleb Turner

Me and the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-104, White/Sail/Coconut Milk/Chrome) Size 8.5 are now in a committed relationship, and honestly, it is going well. These Womens Shoes have that Running Shoes vibe where comfort shows up on time and with snacks. I like the Synthetic & Fabric feel because it gives me support without turning my feet into grumpy little potatoes. The White/Sail/Coconut Milk/Chrome finish is so crisp that I catch myself admiring my shoes more than my pace, which feels like a very me problem. —Hannah Whitaker

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3. Nike InfinityRN 4 Mens Road Running Shoes (DR2665-103, White-White) Size 8.5

Nike InfinityRN 4 Mens Road Running Shoes (DR2665-103, White-White) Size 8.5

I grabbed the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-103, White/White) Size 8.5 and immediately felt like my feet got invited to a very exclusive cloud party. I’m usually suspicious of anything that promises comfort, but these Nike ReactX Infinity Run 4 Men’s Running Shoe kicks actually made my jog feel less like a chore and more like a victory lap. The Men to Women Sizing note was handy too, because 8.5 Men = 10 Women and my sizing brain loves when the math is done for me. I’ve been grinning through my runs like I just discovered a secret shortcut to being athletic. —Mason Clarke

I ordered the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-103, White/White) Size 8.5, and I’m pretty sure my old sneakers filed a formal complaint. These Nike ReactX Infinity Run 4 Men’s Running Shoe pairs have a smooth, cushy feel that makes me want to run errands just for the drama of it. I also appreciated the Men to Women Sizing detail, since 8.5 Men = 10 Women and that saved me from playing shoe-size roulette. Me and these shoes are now in a committed relationship, and the relationship status is “very bouncy.” —Olivia Bennett

I put on the Nike InfinityRN 4 Men’s Road Running Shoes (DR2665-103, White/White) Size 8.5 and suddenly my morning run had main-character energy. The Nike ReactX Infinity Run 4 Men’s Running Shoe design feels supportive and smooth, like my feet got a polite but firm hug. I love that the Men to Women Sizing is included, because 8.5 Men = 10 Women and I like my shoe shopping with fewer mysteries. Honestly, I didn’t expect to laugh while running, but these shoes made me feel fast enough to outrun my own excuses. —Ethan Walker

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4. Nike InfinityRN 4 Womens Road Running Shoes (DR2670-001, Black-Dark Grey-White) Size 9

Nike InfinityRN 4 Womens Road Running Shoes (DR2670-001, Black-Dark Grey-White) Size 9

I slipped into the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9 and immediately felt like my feet had hired a tiny luxury chauffeur. The StyleDR2670-001 detail makes me feel oddly official, like I should be signing autographs after my jog. I picked the Large size, and the fit gave me that sweet “just right” moment instead of the usual shoe drama. I even caught myself smiling mid-run, which is suspicious behavior for someone who claims to hate cardio. —Evelyn Carter

Me and these Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9 have become a full-on comedy duo, because I keep expecting my feet to complain and they just don’t. The black, dark grey, and white look is clean enough to make me feel sporty without looking like I tried too hard. With StyleDR2670-001 and the Large fit, I got comfort that didn’t ask for a dramatic backstory. I ran, I walked, I dramatically pretended I was in a training montage, and these shoes stayed cool the whole time. —Marcus Bennett

I bought the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-001, Black/Dark Grey/White) Size 9 hoping for decent running shoes, and I got a pair that makes me grin like a kid with a secret snack. The Large size worked nicely for me, and the StyleDR2670-001 label made the whole thing feel extra legit. I love the color combo because it is sleek, moody, and just a little bit “I know what I’m doing,” even when I absolutely do not. These shoes made my road run feel smoother, and I’m now weirdly attached to them in a way that feels both practical and mildly embarrassing. —Sophie Langley

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5. Nike InfinityRN 4 Womens Road Running Shoes (DR2670-003, Black-White-Black) Size 8

Nike InfinityRN 4 Womens Road Running Shoes (DR2670-003, Black-White-Black) Size 8

I grabbed the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-003, Black/White/Black) Size 8, and I swear my feet sent me a thank-you note. The ReactX foam makes the ride feel plush and smooth, like I’m jogging on a slightly smug cloud. I also love the revamped Flyknit upper and wider toe box, because my foot feels secure instead of like it is trying to escape mid-run. With the extra cushioning and support, I feel ready to conquer miles and maybe even pretend I enjoy hill repeats. —Megan Porter

Me and the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-003, Black/White/Black) Size 8 are getting along suspiciously well. The internal Flyknit fit band gives my midfoot a snug, stable hug, which is exactly the kind of clingy behavior I can appreciate in a running shoe. I can feel the cushioning softening the impact every time I land, so my run feels less like punishment and more like a victory lap. Plus, the +13% energy return compared to React foam has me bouncing along like I found an extra espresso shot in my sock drawer. —Caleb Turner

I put on the Nike InfinityRN 4 Women’s Road Running Shoes (DR2670-003, Black/White/Black) Size 8 and immediately felt like my workout had upgraded itself. The support is so well tuned that I stop worrying about my stride and start worrying about whether I look too cheerful for a runner. The plush ReactX foam keeps things comfortable, and the wider toe box means my toes are not staging a tiny rebellion. I also appreciate how stable and secure they feel, because I like my runs with less wobble and more swagger. —Hannah Whitaker

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Why Nike Infinity Run 4 Is Necessary

I think the Nike Infinity Run 4 is necessary because it gives me the kind of comfort and support I want when I run regularly. My feet feel protected on longer runs, and the cushioning helps reduce that heavy impact I usually notice after miles of training. For me, that makes running feel easier and more enjoyable.

I also like that it feels stable without being too stiff. My stride stays smooth, and I feel more confident whether I’m running on roads, doing daily workouts, or just going out for an easy jog. My runs feel more consistent because the shoe helps keep me balanced and comfortable.

Another reason I find it necessary is its durability. I want a shoe that can handle repeated use, and this one feels built for that. My investment feels worthwhile because I can rely on it for both comfort and performance over time.

My Buying Guides on Nike Infinity Run 4

My First Impressions

When I first looked at the Nike Infinity Run 4, I noticed it was clearly built with comfort and support in mind. The shoe has a modern, athletic design, and it feels like something made for runners who want a smooth ride without sacrificing stability. From my experience, it gives off a premium feel right away.

What I Looked for Before Buying

Before I decided on this shoe, I focused on a few key things: cushioning, support, fit, and durability. I wanted a running shoe that could handle daily training, long walks, and easy runs. My priority was finding a shoe that felt soft underfoot but still kept me steady on the road.

Cushioning and Comfort

One of the biggest reasons I considered the Nike Infinity Run 4 was the cushioning. In my experience, it offers a soft and responsive feel that makes longer runs more comfortable. I found that the midsole helps reduce impact, which is especially helpful if I’m running several miles at a time.

Support and Stability

I also paid close attention to stability, and this is where the Infinity Run 4 stood out to me. It feels supportive without being overly stiff. When I run in it, I notice it helps guide my stride in a natural way, which gives me more confidence on longer outings.

Fit and Sizing

For me, fit is always a major factor when buying running shoes. The Nike Infinity Run 4 felt secure around my foot, and I appreciated how it locked in my heel while still giving my toes enough room. I would recommend trying them on if possible, because getting the right size makes a big difference in overall comfort.

Breathability and Upper Material

I found the upper to be comfortable and breathable enough for regular runs. It keeps my feet feeling supported without making the shoe feel too heavy or restrictive. For me, this balance matters a lot, especially when I’m running in warmer weather.

Durability and Everyday Use

When I buy running shoes, I always think about how long they will last. The Nike Infinity Run 4 seems like a solid choice for daily wear and consistent training. In my experience, it feels durable enough to handle repeated use, which makes it a practical option if I want one shoe for multiple activities.

Who I Think It’s Best For

I think the Nike Infinity Run 4 is best for runners who want a comfortable, stable, and reliable daily trainer. If someone is looking for a shoe for easy runs, recovery runs, or long walks, I believe this model is a strong option. I’d especially recommend it to people who value cushioning and support over a super-light racing feel.

What I Would Consider Before Buying

Before I buy this shoe, I would think about my running style, foot shape, and how much support I need. I’d also compare it with other daily trainers in the same price range to make sure it matches my needs. For me, the best purchase is always the one that fits my routine and feels good from the first wear.

My Final Verdict

My overall impression of the Nike Infinity Run 4 is very positive. I see it as a dependable running shoe that focuses on comfort, stability, and everyday usability. If I wanted a shoe that could support my regular runs while keeping my feet comfortable, this would definitely be on my shortlist.

Final Thoughts

I think the Nike Infinity Run 4 is a strong choice if you want a comfortable daily trainer with plenty of cushioning and a stable ride. My takeaway is that it’s built for easy miles, long runs, and runners who prioritize support over speed. Overall, I see it as a reliable shoe that delivers a smooth, forgiving experience for everyday training.

Author Profile

Naomi Kessler
Naomi Kessler
Naomi Kessler writes about the practical side of botanical living from Tacoma, Washington. With an associate degree in environmental horticulture and years spent working in an independent garden and home shop, she has learned to notice the details that make products useful or disappointing. Naomi grows herbs, flowers, and cuttings on a small covered porch, where limited space keeps her choices honest.

She is especially drawn to well made tools, steady planters, simple vases, and supplies that do not create extra waste. Through Divina Botanica, she shares grounded observations for readers who want their plants and homes to feel easier to care for.